Now showing items 1-10 of 61
Clozapine versus typical neuroleptic medication for schizophrenia
Background: Long-term drug treatment of schizophrenia with typical antipsychotics has limitations: 25 to 33% of patients have illnesses that are treatment-resistant. Clozapine is an antipsychotic drug, which is claimed to ...
Fluphenazine (oral) versus atypical antipsychotics for schizophrenia
Background: Fluphenazine is a typical antipsychotic drug from the phenothiazine group of antipsychotics. It has been commonly used in the treatment of schizophrenia, however, with the advent of atypical antipsychotic ...
Acetylsalicylic acid (aspirin) for schizophrenia
This is the protocol for a review and there is no abstract. The objectives are as follows: To investigate the effects of acetylsalicylic acid (aspirin), either as adjunct or stand alone treatment, for schizophrenia. Copyright ...
Effect of olanzapine on clinical and polysomnography profiles in patients with schizophrenia
Acute and short-term administration of olanzapine has a favorable effect on sleep in schizophrenia patients. This study aimed to clarify the effect of olanzapine on polysomnographic profiles of schizophrenia patients during ...
Amisulpride augmentation of clozapine for treatment-refractory schizophrenia: a double-blind, placebo-controlled trial
Background: A second antipsychotic is commonly added to clozapine to treat refractory schizophrenia, notwithstanding the limited evidence to support such practice. Methods: The efficacy and adverse effects of this ...
Risperidone (depot) for schizophrenia
BACKGROUND: Risperidone is the first new generation antipsychotic drug made available in a long-acting injection formulation.
Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia
BACKGROUND: Between 40% and 70% of people with treatment-resistant schizophrenia do not respond to clozapine, despite adequate blood levels. For these people, a number of treatment strategies have emerged, including the ...
Risperidone versus placebo for schizophrenia
Background: Risperidone is the first new-generation antipsychotic drug made available in the market in its generic form. Objectives: To determine the clinical effects, safety and cost-effectiveness of risperidone compared ...
Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial
Background: Very late (aged ≥60 years) onset schizophrenia-like psychosis occurs frequently but no placebo-controlled, randomised trials have assessed the efficacy and risks of antipsychotic treatment. We investigated ...
Clozapine dose for schizophrenia
Background: Schizophrenia and related disorders such as schizophreniform and schizoaffective disorder are serious mental illnesses characterised by profound disruptions in thinking and speech, emotional processes, behaviour ...