Browsing Neurological conditions by Title
Now showing items 1-20 of 98
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A multi-layer network approach to MEG connectivity analysis
(2016)Recent years have shown the critical importance of inter-regional neural network connectivity in supporting healthy brain function. Such connectivity is measurable using neuroimaging techniques such as MEG, however the ... -
Addressing the inverse care law: The role of community paediatric services
(2014)Background: Children's health suffers disproportionately from the effects of poverty. The inverse care law states that those who need care the most are the least likely to receive it. Community paediatricians are well ... -
Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment
(2018)Network connectivity is an integral feature of human brain function, and characterising its maturational trajectory is a critical step towards understanding healthy and atypical neurodevelopment. Here, we used magnetoenc ... -
Analysis of shared heritability in common disorders of the brain
(2018)Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide ... -
Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: Cohort study using a primary care database
(2015)BACKGROUND: Epilepsy is a serious condition which can profoundly affect an individual's life. While there is some evidence to suggest an association between antidepressant use and epilepsy and seizures it is conflicting ... -
Anxiety and avoidance in psychogenic nonepileptic seizures: The role of implicit and explicit anxiety
(2014)This study examined implicit and explicit anxiety in individuals with epilepsy and psychogenic nonepileptic seizures (PNESs) and explored whether these constructs were related to experiential avoidance and seizure frequency. ... -
Assessing mood in patients with multiple sclerosis
(2003)Objective: To assess the validity and reliability of mood measures for use with people with multiple sclerosis (MS).; Design: Four mood measures designed for use with people with communication and cognitive problems were ... -
Assessment and management of cognitive problems in people with multiple sclerosis: A national survey of clinical practice
(2018)BACKGROUND: People diagnosed with Multiple Sclerosis often have cognitive problems. However, it is unclear how cognitive impairment is currently assessed and managed in the UK. AIMS: To understand current clinical practice ... -
Atypical white matter microstructure in left-handed individuals
(2016)Information regarding anatomical connectivity in the human brain can be gathered using diffusion tensor imaging (DTI). Fractional anisotropy (FA) is the most commonly derived value, and reflects how strongly directional ... -
Auditory P300 event-related potential: Normative data in the Indian population
(2018)OBJECTIVE: To generate the normative data of auditory P300 event-related potential for various age groups in the Indian population. MATERIALS AND METHODS: Auditory P300 event-related potentials, using the oddball paradigm, ... -
Axonal degeneration and demyelination following traumatic spinal cord injury: A systematic review and meta-analysis
(2019)The pathophysiology of spinal cord injury (SCI) related processes of axonal degeneration and demyelination are poorly understood. The present systematic review and meta-analysis were performed such to establish quantitative ... -
Behavioural activation treatment for depression in individuals with neurological conditions: A systematic review
(2019)OBJECTIVETo evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations.DATA SOURCESPsycINFO, MEDLINE, CINAHL, ... -
Beyond current research practice: Methodological consideration in MS rehabilitation research (is designing the perfect rehabilitation trial the Holy Grail or a Gordian knot?)
(2019)Rehabilitation is an essential aspect of symptomatic and supportive treatment for people with multiple sclerosis (MS). The number of randomised controlled trials (RCTs) for rehabilitation interventions in MS has increased ... -
Changes in electrophysiological markers of cognitive control after administration of galantamine
(2018)The healthy brain is able to maintain a stable balance between bottom-up sensory processing and top-down cognitive control. The neurotransmitter acetylcholine plays a substantial role in this. Disruption of this balance ... -
Clinical and cost effectiveness of memory rehabilitation following traumatic brain injury: a pragmatic cluster randomized controlled trial
(2019)Objective: To evaluate the clinical and cost effectiveness of a group-based memory rehabilitation programme for people with traumatic brain injury. Design: Multicentre, pragmatic, observer-blinded, randomized controlled ... -
Clinical effectiveness of a pain psychology service within an outpatient secondary care setting
(2015)Purpose - Data gathered from routine clinical settings is complementary to evidence garnered from controlled efficacy trials. The purpose of this paper is to present individual-level analysis of changes in a group of ... -
Clinical outcome of autologous mononuclear cells transplantation for spinal cord injury: A systematic review and meta-analysis
(2014)Background: Cell-based therapies can be used to treat neurological diseases and spinal cord injuries. The aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (BM-MNCs) transplantation ... -
Cognitive functioning in people with epilepsy plus severe learning disabilities: A systematic analysis of predictors of daytime arousal and attention
(1999)In spite of the high prevalence of epilepsy and the importance of preserving cognitive function in people with learning disabilities, this population has received relatively little research attention. This study sets out ... -
Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS)
(2019)OBJECTIVE: To assess the clinical and cost-effectiveness of cognitive rehabilitation for attention and memory problems in people with multiple sclerosis. DESIGN: Multicentre, pragmatic, randomized controlled trial. SETTING: ... -
Conceptual issues in neurodevelopmental disorders: Lives out of synch
(2013)Purpose of review Current revision of the two major psychiatric classification systems has elicited particular comment on neurodevelopmental disorders, which have seen increased provision of specialist clinical services, ...
