Browsing Neurological conditions by Title
Now showing items 12-31 of 98
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Behavioural activation treatment for depression in individuals with neurological conditions: A systematic review
(2019)OBJECTIVETo evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations.DATA SOURCESPsycINFO, MEDLINE, CINAHL, ... -
Beyond current research practice: Methodological consideration in MS rehabilitation research (is designing the perfect rehabilitation trial the Holy Grail or a Gordian knot?)
(2019)Rehabilitation is an essential aspect of symptomatic and supportive treatment for people with multiple sclerosis (MS). The number of randomised controlled trials (RCTs) for rehabilitation interventions in MS has increased ... -
Changes in electrophysiological markers of cognitive control after administration of galantamine
(2018)The healthy brain is able to maintain a stable balance between bottom-up sensory processing and top-down cognitive control. The neurotransmitter acetylcholine plays a substantial role in this. Disruption of this balance ... -
Clinical and cost effectiveness of memory rehabilitation following traumatic brain injury: a pragmatic cluster randomized controlled trial
(2019)Objective: To evaluate the clinical and cost effectiveness of a group-based memory rehabilitation programme for people with traumatic brain injury. Design: Multicentre, pragmatic, observer-blinded, randomized controlled ... -
Clinical effectiveness of a pain psychology service within an outpatient secondary care setting
(2015)Purpose - Data gathered from routine clinical settings is complementary to evidence garnered from controlled efficacy trials. The purpose of this paper is to present individual-level analysis of changes in a group of ... -
Clinical outcome of autologous mononuclear cells transplantation for spinal cord injury: A systematic review and meta-analysis
(2014)Background: Cell-based therapies can be used to treat neurological diseases and spinal cord injuries. The aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (BM-MNCs) transplantation ... -
Cognitive functioning in people with epilepsy plus severe learning disabilities: A systematic analysis of predictors of daytime arousal and attention
(1999)In spite of the high prevalence of epilepsy and the importance of preserving cognitive function in people with learning disabilities, this population has received relatively little research attention. This study sets out ... -
Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS)
(2019)OBJECTIVE: To assess the clinical and cost-effectiveness of cognitive rehabilitation for attention and memory problems in people with multiple sclerosis. DESIGN: Multicentre, pragmatic, randomized controlled trial. SETTING: ... -
Conceptual issues in neurodevelopmental disorders: Lives out of synch
(2013)Purpose of review Current revision of the two major psychiatric classification systems has elicited particular comment on neurodevelopmental disorders, which have seen increased provision of specialist clinical services, ... -
Coping with the challenge of transition in older adolescents with epilepsy
(2002)Chronic illnesses, such as epilepsy, have been shown to have detrimental effects on both psychological adjustment and coping behaviour. Using the process model of coping, these effects were investigated in a patient group ... -
Current role of melatonin in pediatric neurology: Clinical recommendations
(2015)BACKGROUND/PURPOSE: Melatonin, an indoleamine secreted by the pineal gland, plays a key role in regulating circadian rhythm. It has chronobiotic, antioxidant, anti-inflammatory and free radical scavenging properties. METHODS: ... -
Developing a fatigue programme: Protocol for the Nottingham Fatigue After Stroke (NotFAST2) study
(2020)Introduction: Post-stroke fatigue is common and is one of the most distressing symptoms after stroke. It has a negative impact on physical, social and psychological functioning; it is also associated with poor outcomes and ... -
Development of human electrophysiological brain networks
(2018)Functional activity in the human brain is intrinsically organized into independently active, connected brain regions. These networks include sensorimotor systems, as well as higher-order cognitive networks such as the ... -
The diagnostic values of UCH-L1 in traumatic brain injury: A meta-analysis
(2017)Traumatic brain injury (TBI) is a major health concern. The purpose of this study is to identify the diagnostic accuracy of ubiquitin C-terminal hydrolase-L1 (UCH-L1)-a protein biomarker-in comparison with CT-scan findings ... -
Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT-3 performance in multiple sclerosis
(2020)Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. ... -
Effectiveness of cognitive rehabilitation for people with multiple sclerosis: a meta-synthesis of patient perspectives
(2017)While previous randomised controlled trials and meta-analyses offer only limited evidence for the effectiveness of cognitive rehabilitation, qualitative studies examining patient perspectives report more positive outcomes. ... -
The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis
(2017)BACKGROUND: Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating ... -
Effects of intermittent theta burst stimulation applied to the left dorsolateral prefrontal cortex on empathy and impulsivity in healthy adult males
(2018)Impulsivity and empathy are clinically relevant multi-dimensional concepts. Existing evidence suggests the left dorsolateral prefrontal cortex (LDLPFC) plays a crucial role in impulsivity and empathy. However, the ... -
The effects of repetitive transcranial magnetic stimulation on empathy: A systematic review and meta-analysis
(2017)Empathy is a multi-dimensional concept with affective and cognitive components, the latter often referred to as Theory of Mind (ToM). Impaired empathy is prevalent in people with neuropsychiatric disorders, such as personality ...
