Now showing items 1-10 of 17
Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: A pharmacological-challenge fMRI (phMRI) study
Aberrant signalling through central 5-HT<inf>2C</inf> receptor pathways has been implicated in various psychiatric disorders but this has not been amenable to experimental investigation in the absence of a valid in-vivo ...
QTc-interval abnormalities in a forensic population
Background: Antipsychotic drugs have been linked to sudden death among psychiatric patients, with a suggestion that prolongation of the QT-interval detectable on a standard electrocardiogram may be linked to fatal cardiac ...
Critical thinking offers a more person-centred approach to drug treatments
Background: The science supporting use of antipsychotic agents, antidepressants and mood stabilizers is not noncontroversial. There are criticisms of the honesty with which trial data are presented, allegations of common ...
A case report of clozapine augmentation with granulocyte colony stimulating factor (G-CSF)
For some patients clozapine represents the only option for controlling the debilitating symptoms of schizophrenia. More tragic are those cases where previously successful treatment with clozapine is withdrawn as a result ...
A survey of the prescribing of selective serotonin reuptake inhibitors by psychiatrists
Questionnaires were sent to 92 doctors asking them aspects of their antidepressant prescribing; 72 returned them. Sixty had prescribed selective serotonin reuptake inhibitors (SSRIs) in the previous year. The ratio of SSRIs ...