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A retrospective audit assessing clozapine utilisation in a high secure forensic hospital
Background/introduction: People with schizophrenia have increased mortality associated with comorbid physical conditions, socioeconomic factors and elevated suicide rates (Saha et al., 2007). Clozapine is superior to other ...
Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18 year-olds: Managing Adolescent first episode Psychosis: A feasibility study (MAPS)
BACKGROUND: Adolescent-onset psychosis is associated with more severe symptoms and poorer outcomes than adult-onset psychosis. The National Institute for Clinical Excellence (NICE) recommend that adolescents with first ...
A retrospective audit to assess the utilisation of clozapine in a high secure forensic hospital
Poster from the Trent Study Day 2019
Do asian patients require only half of the clozapine dose prescribed for caucasians? A critical overview
Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum ...