Psychosis and schizophrenia
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Acute interventions for aggression and agitation in psychosis: Study protocol for a systematic review network meta-analysis
(2019)INTRODUCTION: Individuals with psychosis may access emergency services due to aggression and agitation. When the de-escalation technique fails to achieve tranquillisation, several pharmacological options are available. ... -
Development and validation of multivariable prediction models of remission, recovery, and quality of life outcomes in people with first episode psychosis: A machine learning approach
(2019)Background: Outcomes for people with first-episode psychosis are highly heterogeneous. Few reliable validated methods are available to predict the outcome for individual patients in the first clinical contact. In this ... -
Acute transient psychotic disorder precipitated by Brexit vote
(2019)A man in his 40s was brought to the accident and emergency department in an acute psychotic state, 3 weeks after the European Union referendum results in the UK were declared. His mental health had deteriorated rapidly ... -
Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange)
(2019)INTRODUCTIONMany patients with psychosis experience everyday social situations as anxiety-provoking. The fears can arise, for example, from paranoia, hallucinations, social anxiety or negative-self beliefs. The fears lead ... -
Zotepine versus placebo for schizophrenia
(2013)This is the protocol for a review and there is no abstract. The objectives are as follows: To review the effects of zotepine compared with placebo for people with schizophrenia or related psychoses. As secondary objectives, ... -
The core deficit of classical schizophrenia: Implications for predicting the functional outcome of psychotic illness and developing effective treatments
(2019)Many people suffering from psychotic illnesses experience persisting impairment of occupational and social function. Evidence assembled since the classical description of schizophrenia over a century ago indicates that ... -
Prison vs. hospital for offenders with psychosis; effects on reoffending
(2019)With research showing a high prevalence of psychosis in prisons, its effective management is essential for clinical and criminal outcomes. In a matched sample of released prisoners and discharged patients with psychosis ... -
Attenuated post-movement beta rebound associated with schizotypal features in healthy people
(2019)Introduction: Schizophrenia and schizotypal personality disorder (SPD) lie on a single spectrum of mental illness and converging evidence suggests similarities in the etiology of the 2 conditions. However, schizotypy is a ... -
Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18 year-olds: Managing Adolescent first episode Psychosis: A feasibility study (MAPS)
(2019)BACKGROUND: Adolescent-onset psychosis is associated with more severe symptoms and poorer outcomes than adult-onset psychosis. The National Institute for Clinical Excellence (NICE) recommend that adolescents with first ... -
A meta-analysis taxonomizing empathy in schizophrenia
(2018)Background: Trait empathy is integral to relationship development and maintenance. Therefore, impairment in this ability can have an adverse effect on many domains of life including social, sexual, and marital. Previous ... -
The lost drugs of schizophrenia
(2019)This is a conference poster from the British Association for Psychopharmacology 2019 Summer Meeting, Manchester, 14-17 July 2019 -
Methylphenidate and the risk of psychosis in adolescents and young adults: a population-based cohort study
(2019)BACKGROUND: There is a clinical concern that prescribing methylphenidate, the most common pharmacological treatment for attention-deficit hyperactivity disorder (ADHD), might increase the risk of psychotic events, particularly ... -
Schizophrenia, violence, clozapine and risperidone: A review
(1996)There is no longer much doubt that there is a small but real association between psychosis and violence directed at others, as well as between psychosis and self-directed violence, including suicide. Schizophrenia and the ... -
Electroconvulsive therapy for treatment-resistant schizophrenia
(2019)Background: Electroconvulsive therapy (ECT) involves the induction of a seizure by the administration of an electrical stimulus via electrodes usually placed bilaterally on the scalp and was introduced as a treatment for ... -
Effects of olanzapine on cytokine profile and brain-derived neurotrophic factor in drug-naive subjects with first-episode psychosis
(2019)Immunological abnormalities have been implicated in schizophrenia. On the other hand, antipsychotics may exert immunomodulatory effects, by triggering pro-inflammatory and anti-inflammatory agents through complex homeostatic ... -
Cognitive behavioral therapy plus standard care versus standard care plus other psychosocial treatments for people with schizophrenia
(2019)Cognitive behavioral therapy (CBT) is a psychosocial treatment that aims to help individuals reevaluate their appraisals of their experiences that can affect their level of distress and problematic behavior. CBT is now ... -
"Brain Connectivity Deviates by Sex and Hemisphere in the First Episode of Schizophrenia"—A Route to the Genetic Basis of Language and Psychosis?
(2019)Schizophrenia is genetic in origin and associated with a fecundity disadvantage. The deficits in schizophrenia have been attributed to variation related to the human capacity for language or brain laterality. How sex ... -
Personal growth in psychosis
(2019)
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