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Individual participant data meta-analyses should not ignore clustering
Objectives: Individual participant data (IPD) meta-analyses often analyze their IPD as if coming from a single study. We compare this approach with analyses that rather account for clustering of patients within studies. ...
Stroke specific vocational rehabilitation (SSVR): A feasibility randomised controlled trial
Introduction: A quarter of UK strokes occur in working age people but fewer than half resume work. Rehabilitation frequently fails to address work needs and evidence for post-stroke vocational rehabilitation is lacking. ...
Clinical and cost-effectiveness of adapted cognitive behaviour therapy for non-cardiac chest pain: A multicentre, randomised controlled trial
Objective To investigate the cost-effectiveness of a modified form of cognitive behavioural therapy (CBT) for recurrent non-cardiac chest pain. Methods We tested the effectiveness and cost-effectiveness of a modified form ...
Cognitive behaviour therapy for non-cardiac pain in the chest (COPIC): A multicentre randomized controlled trial with economic evaluation
BACKGROUND: Most patients with chest pain have nothing wrong with their cardiac function. Psychological forms of treatment for this condition are more likely to be successful than others. METHODS/DESIGN: A two-arm parallel ...